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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319303
Species: Mus musculus
RGD Object: Gene
Symbol: Ppp1r3c
Name: protein phosphatase 1, regulatory subunit 3C
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppp1r3caffects expressionISOPpp1r3c (Rattus norvegicus)6480464CTDEstradiol affects the expression of PPP1R3C mRNAPMID:32145629
Ppp1r3cdecreases expressionISOPpp1r3c (Rattus norvegicus)6480464CTDEstradiol results in decreased expression of PPP1R3C mRNAPMID:35192832
Ppp1r3cdecreases expressionISOPPP1R3C (Homo sapiens)6480464CTDEstradiol results in decreased expression of PPP1R3C mRNAPMID:19619570 PMID:21185374 PMID:31614463
Ppp1r3cmultiple interactionsISOPPP1R3C (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of PPP1R3C mRNA; [Estradiol co-treated with TGFB1 protein] results in increased expression of PPP1R3C mRNAPMID:19619570 PMID:30165855
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