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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1314691
Species: Homo sapiens
RGD Object: Gene
Symbol: FZD7
Name: frizzled class receptor 7
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FZD7affects expressionEXP 6480464CTDEstradiol affects the expression of FZD7 mRNAPMID:14699072
FZD7decreases expressionEXP 6480464CTDEstradiol results in decreased expression of FZD7 mRNAPMID:19167446
FZD7multiple interactionsEXP 6480464CTD[Estradiol co-treated with Progesterone] results in decreased expression of FZD7 mRNA; [Estradiol co-treated with TGFB1 protein] results in increased expression of FZD7 mRNAPMID:20660070 PMID:30165855
FZD7decreases expressionISOFzd7 (Mus musculus)6480464CTDEstradiol results in decreased expression of FZD7 mRNAPMID:25210133
FZD7multiple interactionsISOFzd7 (Mus musculus)6480464CTDESR1 protein promotes the reaction [Estradiol results in decreased expression of FZD7 mRNA]PMID:25210133
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