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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1314570
Species: Mus musculus
RGD Object: Gene
Symbol: Sfxn2
Name: sideroflexin 2
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:13145696480464CTDEstradiol results in increased expression of SFXN2 mRNA

PMID:16474171, PMID:19167446
multiple interactionsISORGD:13061316480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of SFXN2 mRNA

PMID:26496021
multiple interactionsISORGD:13145696480464CTD[Estradiol co-treated with TGFB1 protein] results in decreased expression of SFXN2 mRNA

PMID:30165855
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.