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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309507
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rab30
Name: RAB30, member RAS oncogene family
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rab30increases expressionEXP 6480464CTDEstradiol results in increased expression of RAB30 mRNAPMID:32145629
Rab30affects expressionISORAB30 (Homo sapiens)6480464CTDEstradiol affects the expression of RAB30 mRNAPMID:21826169
Rab30decreases expressionISORAB30 (Homo sapiens)6480464CTDEstradiol results in decreased expression of RAB30 mRNAPMID:21185374
Rab30multiple interactionsISORAB30 (Homo sapiens)6480464CTD[Estradiol co-treated with TGFB1 protein] results in decreased expression of RAB30 mRNA; Estradiol inhibits the reaction [afimoxifene results in increased expression of RAB30 mRNA]PMID:16849584 PMID:30165855
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