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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308198
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fosb
Name: FosB proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fosbaffects expressionISOFosb (Mus musculus)6480464CTDEstradiol affects the expression of FOSB mRNAPMID:15598610
Fosbincreases expressionISOFOSB (Homo sapiens)6480464CTDEstradiol results in increased expression of FOSB mRNAPMID:19153601
Fosbincreases expressionISOFosb (Mus musculus)6480464CTDEstradiol results in increased expression of FOSB mRNAPMID:25210133
Fosbmultiple interactionsISOFOSB (Homo sapiens)6480464CTD[Estradiol co-treated with Progesterone] results in decreased expression of FOSB mRNAPMID:20660070
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