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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306269
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sipa1l2
Name: signal-induced proliferation-associated 1 like 2
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sipa1l2increases expressionISOSIPA1L2 (Homo sapiens)6480464CTDEstradiol results in increased expression of SIPA1L2 mRNAPMID:21795739
Sipa1l2multiple interactionsISOSIPA1L2 (Homo sapiens)6480464CTD[Estradiol co-treated with Norethindrone Acetate] results in increased expression of SIPA1L2 mRNA; Progesterone inhibits the reaction [Estradiol results in increased expression of SIPA1L2 mRNA]PMID:21795739 PMID:22217510
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