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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305859
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Elf5
Name: E74 like ETS transcription factor 5
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Elf5multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of ELF5 mRNA; [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of ELF5 mRNAPMID:26496021 PMID:32741896
Elf5decreases expressionISOELF5 (Homo sapiens)6480464CTDEstradiol results in decreased expression of ELF5 mRNAPMID:24758408
Elf5increases expressionISOELF5 (Homo sapiens)6480464CTDEstradiol results in increased expression of ELF5 mRNAPMID:19619570
Elf5increases expressionISOElf5 (Mus musculus)6480464CTDEstradiol results in increased expression of ELF5 mRNAPMID:19484750
Elf5multiple interactionsISOELF5 (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of ELF5 mRNA; EGF protein promotes the reaction [Estradiol results in decreased expression of ELF5 mRNA]PMID:19619570 PMID:24758408
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