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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10835
Species: Mus musculus
RGD Object: Gene
Symbol: Kcnj8
Name: potassium inwardly-rectifying channel, subfamily J, member 8
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnj8decreases expressionISOKCNJ8 (Homo sapiens)6480464CTDEstradiol results in decreased expression of KCNJ8 mRNAPMID:19619570 PMID:31614463
Kcnj8multiple interactionsISOKCNJ8 (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of KCNJ8 mRNA; [Progesterone co-treated with Estradiol] results in increased expression of KCNJ8 mRNAPMID:17404688 PMID:19619570
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