GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ins2 | increases expression | EXP | | 6480464 | CTD | Estradiol results in increased expression of INS2 protein | PMID:18446233 | Ins2 | multiple interactions | EXP | | 6480464 | CTD | ESR1 protein affects the reaction [Estradiol results in increased expression of INS2 protein]; Estradiol promotes the reaction [Glucose results in increased secretion of INS2 protein]; fulvestrant inhibits the reaction [Estradiol results in increased expression of INS2 protein] | PMID:18446233 | Ins2 | increases expression | ISO | Ins2 (Rattus norvegicus) | 6480464 | CTD | Estradiol results in increased expression of INS2 mRNA | PMID:18446233 | Ins2 | multiple interactions | ISO | INS (Homo sapiens) | 6480464 | CTD | Estradiol promotes the reaction [INS protein results in decreased oxidation of Palmitates]; Estradiol promotes the reaction [INS protein results in increased chemical synthesis of Glycogen] | PMID:21632903 | | ||||||||||||||||||||||
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