GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hsd11b1 | decreases expression | EXP | | 6480464 | CTD | Estradiol results in decreased expression of HSD11B1 mRNA | PMID:19484750 | Hsd11b1 | decreases activity | ISO | Hsd11b1 (Rattus norvegicus) | 6480464 | CTD | Estradiol results in decreased activity of HSD11B1 protein | PMID:23814014 | Hsd11b1 | increases expression | ISO | Hsd11b1 (Rattus norvegicus) | 6480464 | CTD | Estradiol results in increased expression of HSD11B1 mRNA; Estradiol results in increased expression of HSD11B1 protein | PMID:32145629 | Hsd11b1 | multiple interactions | ISO | HSD11B1 (Homo sapiens) | 6480464 | CTD | [Estradiol co-treated with NAD] binds to HSD11B1 protein; [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of HSD11B1 protein | PMID:23275455 PMID:25526675 | | ||||||||||||||||||||||
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