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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10708
Species: Mus musculus
RGD Object: Gene
Symbol: Hgf
Name: hepatocyte growth factor
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hgfdecreases expressionEXP 6480464CTDEstradiol results in decreased expression of HGF mRNAPMID:25210133
Hgfdecreases expressionISOHgf (Rattus norvegicus)6480464CTDEstradiol results in decreased expression of HGF mRNAPMID:31119341
Hgfincreases expressionISOHgf (Rattus norvegicus)6480464CTDEstradiol results in increased expression of HGF mRNAPMID:32145629
Hgfmultiple interactionsISOHgf (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Estradiol] results in increased expression of HGF mRNA; [Testosterone co-treated with Estradiol] results in increased expression of HGF mRNAPMID:26496021 PMID:32741896
Hgfmultiple interactionsISOHGF (Homo sapiens)6480464CTD[Estradiol co-treated with Progesterone] results in decreased expression of HGF mRNA; [Progesterone co-treated with Estradiol] results in decreased expression of HGF mRNAPMID:17404688 PMID:20660070
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