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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10586
Species: Mus musculus
RGD Object: Gene
Symbol: Fgg
Name: fibrinogen gamma chain
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fggdecreases expressionEXP 6480464CTDEstradiol results in decreased expression of FGG mRNAPMID:19484750
Fggdecreases expressionISOFgg (Rattus norvegicus)6480464CTDEstradiol results in decreased expression of FGG proteinPMID:32145629
Fggmultiple interactionsISOFgg (Rattus norvegicus)6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of FGG mRNA; [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of FGG mRNAPMID:26496021 PMID:32741896
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