GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Akr1c18 | increases metabolic processing | ISO | AKR1C3 (Homo sapiens) | 6480464 | CTD | AKR1C3 protein results in increased metabolism of Androstenedione | PMID:19010312 | Akr1c18 | increases reduction | ISO | AKR1C3 (Homo sapiens) | 6480464 | CTD | AKR1C3 protein results in increased reduction of Androstenedione | PMID:17950253 PMID:20036328 | Akr1c18 | multiple interactions | ISO | AKR1C3 (Homo sapiens) | 6480464 | CTD | [AKR1C3 protein results in increased metabolism of Androstenedione] which results in increased chemical synthesis of Dihydrotestosterone; [AKR1C3 protein results in increased metabolism of Androstenedione] which results in increased chemical synthesis of Testosterone; [AKR1C3 protein results in increased reduction of Androstenedione] which results in increased chemical synthesis of Testosterone; Indomethacin analog inhibits the reaction [AKR1C3 protein results in increased reduction of Androstenedione]; Indomethacin inhibits the reaction [AKR1C3 protein results in increased reduction of Androstenedione]; N-(4-chlorobenzoyl)melatonin inhibits the reaction [AKR1C3 protein results in increased reduction of Androstenedione] | PMID:17950253 PMID:19010312 PMID:20036328 | | ||||||||||||||||||||||
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