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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557417
Species: Mus musculus
RGD Object: Gene
Symbol: Gdf3
Name: growth differentiation factor 3
Acc ID: CHEBI:164200
Term: triclosan
Definition: An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.
Chemical ID: MESH:D014260
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gdf3multiple interactionsISOGDF3 (Homo sapiens)6480464CTDTriclosan inhibits the reaction [Lipopolysaccharides results in increased expression of GDF3 mRNA]PMID:20507366
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