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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736761
Species: Mus musculus
RGD Object: Gene
Symbol: Atf2
Name: activating transcription factor 2
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atf2increases phosphorylationEXP 6480464CTDLipopolysaccharides results in increased phosphorylation of ATF2 proteinPMID:23256447
Atf2multiple interactionsEXP 6480464CTD[Drugs, Chinese Herbal co-treated with niuhuang] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of ATF2 protein]; Lipopolysaccharides results in increased phosphorylation of and results in increased activity of ATF2 proteinPMID:23106696 PMID:23256447
Atf2increases phosphorylationISOAtf2 (Rattus norvegicus)6480464CTDLipopolysaccharides results in increased phosphorylation of ATF2 proteinPMID:24312512
Atf2multiple interactionsISOAtf2 (Rattus norvegicus)6480464CTDbaicalin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of ATF2 protein]PMID:24312512
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