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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733492
Species: Mus musculus
RGD Object: Gene
Symbol: Ltc4s
Name: leukotriene C4 synthase
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ltc4sdecreases expressionEXP 6480464CTDLipopolysaccharides results in decreased expression of LTC4S mRNAPMID:21461237
Ltc4sdecreases expressionISOLTC4S (Homo sapiens)6480464CTDLipopolysaccharides results in decreased expression of LTC4S mRNAPMID:12574384
Ltc4smultiple interactionsISOLTC4S (Homo sapiens)6480464CTDparthenolide inhibits the reaction [Lipopolysaccharides results in decreased expression of LTC4S mRNA]; TLR4 protein affects the reaction [Lipopolysaccharides results in decreased expression of LTC4S mRNA]PMID:12574384
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