Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733199
Species: Mus musculus
RGD Object: Gene
Symbol: Top1
Name: topoisomerase (DNA) I
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Top1increases expressionEXP 6480464CTDLipopolysaccharides results in increased expression of TOP1 mRNAPMID:10975854
Top1multiple interactionsISOTOP1 (Homo sapiens)6480464CTD[Lipopolysaccharides co-treated with resveratrol] results in decreased expression of TOP1 mRNAPMID:26667767
Go Back to source page   Continue to Ontology report