GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Csf3 | decreases expression | EXP | | 6480464 | CTD | Lipopolysaccharides results in decreased expression of CSF3 mRNA | PMID:12057914 | Csf3 | increases expression | EXP | | 6480464 | CTD | Lipopolysaccharides results in increased expression of CSF3 mRNA; Lipopolysaccharides results in increased expression of CSF3 protein | PMID:19133137 PMID:20423518 PMID:22687549 PMID:25843059 PMID:26790433 | Csf3 | increases secretion | EXP | | 6480464 | CTD | Lipopolysaccharides results in increased secretion of CSF3 protein | PMID:32800949 | Csf3 | multiple interactions | EXP | | 6480464 | CTD | 3,4-dihydroxybenzohydroxamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]; [Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CSF3 protein; genipin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]; IL6 protein affects the reaction [Lipopolysaccharides results in increased secretion of CSF3 protein]; mangiferin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CSF3 protein]; phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]; Polymyxin B inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]; terameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein] | PMID:15135318 PMID:15804595 PMID:19133137 PMID:20423518 PMID:22687549 PMID:25843059 PMID:26790433 | Csf3 | increases expression | ISO | CSF3 (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in increased expression of CSF3 mRNA; Lipopolysaccharides results in increased expression of CSF3 protein | PMID:24707119 PMID:35811015 | Csf3 | increases expression | ISO | Csf3 (Rattus norvegicus) | 6480464 | CTD | Lipopolysaccharides results in increased expression of CSF3 mRNA; Lipopolysaccharides results in increased expression of CSF3 protein | PMID:18710323 PMID:33727093 | Csf3 | increases secretion | ISO | CSF3 (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in increased secretion of CSF3 protein | PMID:32800949 | Csf3 | multiple interactions | ISO | CSF3 (Homo sapiens) | 6480464 | CTD | 2'-hydroxyflavanone inhibits the reaction [Lipopolysaccharides results in increased secretion of CSF3 protein]; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF3 mRNA; [nickel chloride co-treated with Lipopolysaccharides] results in increased secretion of CSF3 protein; [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in increased expression of CSF3 mRNA; hesperetin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]; Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]; Resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein]; S-(1,2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]; Silymarin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein] | PMID:18437699 PMID:24707119 PMID:32800949 PMID:35811015 PMID:9122163 | Csf3 | multiple interactions | ISO | Csf3 (Rattus norvegicus) | 6480464 | CTD | [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CSF3 mRNA; Heparin inhibits the reaction [[Lipopolysaccharides co-treated with Ranitidine] results in increased expression of CSF3 mRNA]; Triglycerides promotes the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA] | PMID:16401727 PMID:18710323 | |
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