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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70896
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ces1d
Name: carboxylesterase 1D
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ces1ddecreases expressionISOCES1 (Homo sapiens)6480464CTDLipopolysaccharides results in decreased expression of CES1 mRNA; Lipopolysaccharides results in decreased expression of CES1 proteinPMID:21237253
Ces1ddecreases expressionISOCes1d (Mus musculus)6480464CTDLipopolysaccharides results in decreased expression of CES1D mRNAPMID:27339419
Ces1dmultiple interactionsISOCES1 (Homo sapiens)6480464CTDprolinedithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CES1 mRNA]; SB 203580 inhibits the reaction [Lipopolysaccharides results in decreased expression of CES1 mRNA]PMID:21237253
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