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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621828
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Khsrp
Name: KH-type splicing regulatory protein
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Khsrpmultiple interactionsISOKhsrp (Mus musculus)6480464CTDKHSRP gene mutant form inhibits the reaction [resveratrol inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of CXCL1 mRNA]]; KHSRP gene mutant form inhibits the reaction [resveratrol inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of NOS2 mRNA]]; KHSRP gene mutant form inhibits the reaction [resveratrol inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]]; KHSRP gene mutant form promotes the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of CXCL1 mRNA]; KHSRP gene mutant form promotes the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of NOS2 mRNA]; KHSRP gene mutant form promotes the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]PMID:25352548
Khsrpmultiple interactionsISOKHSRP (Homo sapiens)6480464CTD[NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of KHSRP mRNAPMID:35877022
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