GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Socs3 | increases expression | ISO | SOCS3 (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in increased expression of SOCS3 mRNA | PMID:18192897 PMID:18453621 PMID:25725100 PMID:35811015 | Socs3 | increases expression | ISO | Socs3 (Mus musculus) | 6480464 | CTD | Lipopolysaccharides results in increased expression of SOCS3 mRNA | PMID:22024136 PMID:22169119 PMID:22185406 PMID:25890327 PMID:26918785 PMID:27339419 | Socs3 | multiple interactions | ISO | SOCS3 (Homo sapiens) | 6480464 | CTD | (+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of SOCS3 mRNA]; [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in increased expression of SOCS3 mRNA; S-(1,2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of SOCS3 mRNA] | PMID:25725100 PMID:35811015 | Socs3 | multiple interactions | ISO | Socs3 (Mus musculus) | 6480464 | CTD | (+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of SOCS3 mRNA]; [Resveratrol co-treated with Lipopolysaccharides] results in increased expression of SOCS3 protein; bardoxolone methyl inhibits the reaction [Lipopolysaccharides results in increased expression of SOCS3 mRNA]; Eicosapentaenoic Acid promotes the reaction [Lipopolysaccharides results in increased expression of SOCS3 mRNA]; IL10 protein affects the reaction [[Resveratrol co-treated with Lipopolysaccharides] results in increased expression of SOCS3 protein]; IL10 protein promotes the reaction [Lipopolysaccharides results in increased expression of SOCS3 mRNA]; Quercetin inhibits the reaction [Lipopolysaccharides results in increased expression of SOCS3 mRNA]; tocotrienol, delta inhibits the reaction [Lipopolysaccharides results in increased expression of SOCS3 mRNA] | PMID:22024136 PMID:22169119 PMID:22185406 PMID:25576658 PMID:25890327 PMID:26918785 | |
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