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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619908
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Braf
Name: B-Raf proto-oncogene, serine/threonine kinase
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Brafincreases phosphorylationISOBraf (Mus musculus)6480464CTDLipopolysaccharides results in increased phosphorylation of BRAF proteinPMID:19540866
Brafmultiple interactionsISOBraf (Mus musculus)6480464CTDKetamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of BRAF protein]PMID:19540866
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