GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cxcr2 | decreases expression | ISO | CXCR2 (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in decreased expression of CXCR2 mRNA; Lipopolysaccharides results in decreased expression of CXCR2 protein | PMID:10950785 PMID:11531949 PMID:14997032 PMID:26111115 PMID:35811015 | Cxcr2 | increases expression | ISO | CXCR2 (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in increased expression of CXCR2 protein | PMID:26111115 | Cxcr2 | multiple interactions | ISO | CXCR2 (Homo sapiens) | 6480464 | CTD | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of CXCR2 mRNA; [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of CXCR2 mRNA; doramapimod inhibits the reaction [Lipopolysaccharides results in decreased expression of CXCR2 protein]; SB 203580 inhibits the reaction [Lipopolysaccharides results in decreased expression of CXCR2 protein] | PMID:10950785 PMID:14997032 PMID:35811015 | |
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