GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Egr1 | increases expression | EXP | | 6480464 | CTD | Lipopolysaccharides results in increased expression of EGR1 mRNA | PMID:16415329 | Egr1 | multiple interactions | EXP | | 6480464 | CTD | [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of EGR1 mRNA; Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of EGR1 mRNA] | PMID:16401727 PMID:16415329 | Egr1 | affects localization | ISO | Egr1 (Mus musculus) | 6480464 | CTD | Lipopolysaccharides affects the localization of EGR1 protein | PMID:25451575 | Egr1 | decreases expression | ISO | Egr1 (Mus musculus) | 6480464 | CTD | Lipopolysaccharides results in decreased expression of EGR1 mRNA | PMID:27339419 | Egr1 | increases expression | ISO | Egr1 (Mus musculus) | 6480464 | CTD | Lipopolysaccharides results in increased expression of EGR1 mRNA; Lipopolysaccharides results in increased expression of EGR1 protein | PMID:10975854 PMID:22046279 PMID:23107598 PMID:25843059 | Egr1 | multiple interactions | ISO | Egr1 (Mus musculus) | 6480464 | CTD | 3,4-dihydroxybenzohydroxamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of EGR1 mRNA]; Carbon Monoxide inhibits the reaction [Lipopolysaccharides results in increased expression of EGR1 mRNA]; Carbon Monoxide inhibits the reaction [Lipopolysaccharides results in increased expression of EGR1 protein]; Indirubin E804 inhibits the reaction [Lipopolysaccharides results in increased expression of EGR1 mRNA]; Lipopolysaccharides inhibits the reaction [Indirubin E804 results in increased expression of EGR1 mRNA]; PPARG protein promotes the reaction [Lipopolysaccharides results in increased expression of EGR1 mRNA]; SB 203580 inhibits the reaction [Lipopolysaccharides results in increased expression of EGR1 mRNA]; U 0126 inhibits the reaction [Lipopolysaccharides results in increased expression of EGR1 protein]; UCP2 protein promotes the reaction [Carbon Monoxide inhibits the reaction [Lipopolysaccharides results in increased expression of EGR1 protein]] | PMID:22046279 PMID:23107598 PMID:25843059 | | ||||||||||||||||||||||
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