GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Agt | decreases expression | EXP | | 6480464 | CTD | Lipopolysaccharides results in decreased expression of AGT protein | PMID:19118600 | Agt | increases expression | EXP | | 6480464 | CTD | Lipopolysaccharides results in increased expression of AGT mRNA; Lipopolysaccharides results in increased expression of AGT protein; Lipopolysaccharides results in increased expression of AGT protein alternative form | PMID:12575980 PMID:27302421 | Agt | multiple interactions | EXP | | 6480464 | CTD | 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [ACE2 protein inhibits the reaction [Lipopolysaccharides results in increased expression of AGT protein]]; 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [ACE2 protein promotes the reaction [Lipopolysaccharides results in increased expression of AGT protein alternative form]]; 7-Ala-angiotensin (1-7) inhibits the reaction [ACE2 protein inhibits the reaction [Lipopolysaccharides results in increased expression of AGT protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [ACE2 protein promotes the reaction [Lipopolysaccharides results in increased expression of AGT protein alternative form]]; ACE2 protein inhibits the reaction [Lipopolysaccharides results in increased expression of AGT protein]; ACE2 protein promotes the reaction [Lipopolysaccharides results in increased expression of AGT protein alternative form]; AGT protein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; candesartan inhibits the reaction [AGT protein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]] | PMID:10525314 PMID:27302421 | Agt | increases expression | ISO | AGT (Homo sapiens) | 6480464 | CTD | Lipopolysaccharides results in increased expression of AGT protein; Lipopolysaccharides results in increased expression of AGT protein alternative form | PMID:26862037 | Agt | multiple interactions | ISO | Agt (Mus musculus) | 6480464 | CTD | AGT protein modified form promotes the reaction [FXN gene mutant form promotes the reaction [Lipopolysaccharides results in increased expression of AIF1 protein]]; AGT protein modified form promotes the reaction [FXN gene mutant form promotes the reaction [Lipopolysaccharides results in increased expression of GFAP protein]] | PMID:26954031 | Agt | multiple interactions | ISO | AGT (Homo sapiens) | 6480464 | CTD | 7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGT protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [diminazene aceturate promotes the reaction [Lipopolysaccharides results in increased expression of AGT protein alternative form]]; ACE2 protein affects the reaction [diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGT protein]]; ACE2 protein affects the reaction [diminazene aceturate promotes the reaction [Lipopolysaccharides results in increased expression of AGT protein alternative form]]; diminazene aceturate inhibits the reaction [Lipopolysaccharides results in increased expression of AGT protein]; diminazene aceturate promotes the reaction [Lipopolysaccharides results in increased expression of AGT protein alternative form] | PMID:26862037 | | ||||||||||||||||||||||
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