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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1594557
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cfp
Name: complement factor properdin
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cfpincreases expressionISORGD:15577206480464CTDLipopolysaccharides results in increased expression of CFP mRNA

PMID:27339419
Cfpmultiple interactionsISORGD:15577206480464CTDCFP gene mutant form inhibits the reaction [Lipopolysaccharides results in increased expression of C3 protein]

PMID:17916747
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.