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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1553064
Species: Mus musculus
RGD Object: Gene
Symbol: Fasl
Name: Fas ligand
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Faslincreases expressionEXP 6480464CTDLipopolysaccharides results in increased expression of FASL mRNA; Lipopolysaccharides results in increased expression of FASLG mRNAPMID:12057914 PMID:9657385
Faslincreases expressionISOFaslg (Rattus norvegicus)6480464CTDLipopolysaccharides results in increased expression of FASLG proteinPMID:31486215
Faslmultiple interactionsISOFASLG (Homo sapiens)6480464CTD[usnic acid co-treated with Lipopolysaccharides] results in decreased expression of FASLG mRNAPMID:22777745
Faslmultiple interactionsISOFaslg (Rattus norvegicus)6480464CTDHonghua extract, Carthamus tinctorius inhibits the reaction [Lipopolysaccharides results in increased expression of FASLG protein]PMID:31486215
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