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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 14272472
Species: Sus scrofa
RGD Object: Gene
Symbol: RELA
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
RELAincreases phosphorylationEXP 6480464CTDLipopolysaccharides results in increased phosphorylation of RELA proteinPMID:28528741 PMID:32877744
RELAmultiple interactionsEXP 6480464CTD[deoxynivalenol co-treated with Lipopolysaccharides] affects the localization of RELA protein; [Flavones co-treated with Lipopolysaccharides] results in increased phosphorylation of RELA protein; deoxynivalenol promotes the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]; ochratoxin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]PMID:28528741 PMID:31669396 PMID:32877744
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