GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ITGAM | increases expression | EXP | | 11061443 | RGD | Lipopolysaccharide increases expression of ITGAM protein on neutrophils and monocytes | | ITGAM | increases expression | EXP | | 329853765 | RGD | Lipopolysaccharide increases expression of ITGAM protein on neutrophils | | ITGAM | increases expression | EXP | | 6480464 | CTD | Lipopolysaccharides results in increased expression of ITGAM; Lipopolysaccharides results in increased expression of ITGAM protein | PMID:12734376 PMID:18639531 PMID:21045076 | ITGAM | increases expression | ISO | Itgam (Rattus norvegicus) | 6480464 | CTD | Lipopolysaccharides results in increased expression of ITGAM; Lipopolysaccharides results in increased expression of ITGAM protein | PMID:17655881 PMID:22903158 PMID:25447322 PMID:28693884 | ITGAM | increases expression | ISO | Itgam (Mus musculus) | 6480464 | CTD | Lipopolysaccharides results in increased expression of ITGAM protein | PMID:15328337 PMID:19374788 PMID:21575647 PMID:23376802 PMID:25047101 PMID:8566054 | ITGAM | multiple interactions | ISO | Itgam (Rattus norvegicus) | 6480464 | CTD | Estrone inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAM protein]; ginsenoside Rb1 inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAM protein]; Lipopolysaccharides inhibits the reaction [Rutin results in increased expression of ITGAM protein]; notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAM protein] | PMID:17655881 PMID:22903158 PMID:28693884 | ITGAM | multiple interactions | ISO | Itgam (Mus musculus) | 6480464 | CTD | [FXN gene mutant form results in increased susceptibility to Lipopolysaccharides] which results in increased expression of ITGAM protein; [Lipopolysaccharides co-treated with IFNG protein] results in increased expression of ITGAM protein; Fluoxetine inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAM protein]; ITGAM protein affects the reaction [Lipopolysaccharides affects the localization of and results in increased activity of [NFKB1 protein binds to RELA protein]]; ITGAM protein affects the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA]; ITGAM protein affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; ITGAM protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]; ITGAM protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]; ITGAM protein affects the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]; ITGAM protein affects the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]; ML 7 inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAM protein]; sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of ITGAM protein]; tepoxalin inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAM protein]; zileuton inhibits the reaction [Lipopolysaccharides results in increased expression of ITGAM protein] | PMID:11123339 PMID:15328337 PMID:19374788 PMID:21575647 PMID:26954031 PMID:36988325 PMID:8566054 | | ||||||||||||||||||||||
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