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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1343432
Species: Homo sapiens
RGD Object: Gene
Symbol: SERPINB2
Name: serpin family B member 2
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SERPINB2increases expressionEXP 6480464CTDLipopolysaccharides results in increased expression of SERPINB2 mRNA; Lipopolysaccharides results in increased expression of SERPINB2 proteinPMID:18289624 PMID:35811015
SERPINB2multiple interactionsEXP 6480464CTDochratoxin A inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINB2 mRNA]; ochratoxin A inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINB2 protein]; S-(1,2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINB2 mRNA]PMID:18289624 PMID:35811015
SERPINB2increases expressionISOSerpinb2 (Mus musculus)6480464CTDLipopolysaccharides results in increased expression of SERPINB2 mRNAPMID:12057914
SERPINB2multiple interactionsISOSerpinb2 (Mus musculus)6480464CTD[Silicon Dioxide co-treated with Lipopolysaccharides] results in increased expression of SERPINB2 mRNA; AHR protein affects the reaction [[Silicon Dioxide co-treated with Lipopolysaccharides] results in increased expression of SERPINB2 mRNA]; CASP1 protein affects the reaction [AHR protein affects the reaction [[Silicon Dioxide co-treated with Lipopolysaccharides] results in increased expression of SERPINB2 mRNA]]PMID:22273745
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