Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310734
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pla2g7
Name: phospholipase A2 group VII
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pla2g7increases activityEXP 6480464CTDLipopolysaccharides results in increased activity of PLA2G7 proteinPMID:10409262
Pla2g7increases expressionEXP 6480464CTDLipopolysaccharides results in increased expression of PLA2G7 mRNAPMID:10409262
Pla2g7increases activityISOPla2g7 (Mus musculus)6480464CTDLipopolysaccharides results in increased activity of PLA2G7 proteinPMID:10409262
Pla2g7increases expressionISOPLA2G7 (Homo sapiens)6480464CTDLipopolysaccharides results in increased expression of PLA2G7 mRNAPMID:21176638
Pla2g7increases expressionISOPla2g7 (Mus musculus)6480464CTDLipopolysaccharides results in increased expression of PLA2G7 mRNAPMID:27339419
Pla2g7multiple interactionsISOPLA2G7 (Homo sapiens)6480464CTDLipopolysaccharides results in increased expression of and results in increased activity of PLA2G7 protein; SB 203580 inhibits the reaction [Lipopolysaccharides results in increased expression of PLA2G7 protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G7 protein]; Simvastatin inhibits the reaction [Lipopolysaccharides results in increased expression of PLA2G7 mRNA]PMID:21176638
Go Back to source page   Continue to Ontology report