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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309378
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Scap
Name: SREBF chaperone
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scapincreases expressionEXP 6480464CTDLipopolysaccharides results in increased expression of SCAP proteinPMID:33677747
Scapmultiple interactionsEXP 6480464CTDethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Lipopolysaccharides results in increased expression of SCAP protein]PMID:33677747
Scapincreases expressionISOSCAP (Homo sapiens)6480464CTDLipopolysaccharides results in increased expression of SCAP proteinPMID:33677747
Scapmultiple interactionsISOSCAP (Homo sapiens)6480464CTDMIR590 mRNA inhibits the reaction [Lipopolysaccharides results in increased expression of SCAP protein]PMID:33677747
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