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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10991
Species: Mus musculus
RGD Object: Gene
Symbol: Nos1
Name: nitric oxide synthase 1, neuronal
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos1multiple interactionsEXP 6480464CTD[[Industrial Waste results in increased abundance of Water Pollutants] which co-treated with naphthenic acid] inhibits the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased expression of NOS1 mRNA]; [Lipopolysaccharides co-treated with IFNG] results in increased expression of NOS1 mRNA; Ozone inhibits the reaction [[[Industrial Waste results in increased abundance of Water Pollutants] which co-treated with naphthenic acid] inhibits the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased expression of NOS1 mRNA]]; Resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS]PMID:21940034 PMID:23921197
Nos1increases expressionISONOS1 (Homo sapiens)6480464CTDLipopolysaccharides results in increased expression of NOS1 proteinPMID:17855475
Nos1multiple interactionsISONOS1 (Homo sapiens)6480464CTDN-(4-O-glycerol-3-methoxybenzyl)nonivamide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS1 protein]PMID:17855475
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