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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1616522
Species: Mus musculus
RGD Object: Gene
Symbol: Pde11a
Name: phosphodiesterase 11A
Acc ID: CHEBI:16356
Term: 3',5'-cyclic GMP
Definition: A 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine.
Chemical ID: MESH:D006152
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pde11aincreases hydrolysisISOPDE11A (Homo sapiens)6480464CTDPDE11A protein results in increased hydrolysis of Cyclic GMPPMID:10725373
Pde11amultiple interactionsISOPDE11A (Homo sapiens)6480464CTD1-Methyl-3-isobutylxanthine inhibits the reaction [PDE11A protein results in increased hydrolysis of Cyclic GMP]; Dipyridamole inhibits the reaction [PDE11A protein results in increased hydrolysis of Cyclic GMP]; zaprinast inhibits the reaction [PDE11A protein results in increased hydrolysis of Cyclic GMP]PMID:10725373
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