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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621747
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gsr
Name: glutathione-disulfide reductase
Acc ID: CHEBI:16348
Term: 3-nitropropanoic acid
Definition: A C-nitro compound that is propanoic acid in which one of the methyl hydrogens has been replaced by a nitro group.
Chemical ID: MESH:C015392
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gsrdecreases activityEXP 6480464CTD3-nitropropionic acid results in decreased activity of GSR proteinPMID:21945202 PMID:27206696 PMID:37116597
Gsrmultiple interactionsEXP 6480464CTDnaringin inhibits the reaction [3-nitropropionic acid results in decreased activity of GSR protein]; thymoquinone analog inhibits the reaction [3-nitropropionic acid results in decreased activity of GSR protein]; thymoquinone inhibits the reaction [3-nitropropionic acid results in decreased activity of GSR protein]PMID:21945202 PMID:27206696
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