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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732740
Species: Homo sapiens
RGD Object: Gene
Symbol: CAT
Name: catalase
Acc ID: CHEBI:16347
Term: (R)-carnitine
Definition: The (R)-enantiomer of carnitine.
Chemical ID: MESH:D002331
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CATmultiple interactionsISOCat (Rattus norvegicus)6480464CTDCarnitine inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein]; Carnitine inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]; Carnitine inhibits the reaction [Ifosfamide results in decreased expression of CAT mRNA]PMID:16889571 PMID:19294768 PMID:23213347
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