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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1354298
Species: Homo sapiens
RGD Object: Gene
Symbol: PDIA6
Name: protein disulfide isomerase family A member 6
Acc ID: CHEBI:16336
Term: hyaluronic acid
Definition: A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells.
Chemical ID: MESH:D006820
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PDIA6multiple interactionsISOPdia6 (Rattus norvegicus)6480464CTDHyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of PDIA6 protein]PMID:23178681
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