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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62192
Species: Mus musculus
RGD Object: Gene
Symbol: Slc29a1
Name: solute carrier family 29 (nucleoside transporters), member 1
Acc ID: CHEBI:16335
Term: adenosine
Definition: A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond.
Chemical ID: MESH:D000241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc29a1affects abundanceEXP 6480464CTDSLC29A1 affects the abundance of AdenosinePMID:21872611
Slc29a1increases uptakeEXP 6480464CTDSLC29A1 protein alternative form results in increased uptake of Adenosine; SLC29A1 protein results in increased uptake of AdenosinePMID:11179696
Slc29a1multiple interactionsEXP 6480464CTD4-nitrobenzylthioinosine inhibits the reaction [SLC29A1 protein alternative form results in increased uptake of Adenosine]; 4-nitrobenzylthioinosine inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; [4-nitrobenzylthioinosine results in decreased activity of SLC29A1 protein] inhibits the reaction [Oxygen deficiency results in increased abundance of Adenosine]; [SLC29A1 co-treated with Oxygen deficiency] affects the abundance of Adenosine; Dipyridamole inhibits the reaction [SLC29A1 protein alternative form results in increased uptake of Adenosine]; Dipyridamole inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Dipyridamole promotes the reaction [[SLC29A1 co-treated with Oxygen deficiency] affects the abundance of Adenosine]PMID:11179696 PMID:21872611 PMID:23437309
Slc29a1increases uptakeISOSLC29A1 (Homo sapiens)6480464CTDSLC29A1 protein alternative form results in increased uptake of Adenosine; SLC29A1 protein results in increased uptake of AdenosinePMID:21283641 PMID:28041785 PMID:9396714
Slc29a1multiple interactionsISOSlc29a1 (Rattus norvegicus)6480464CTDAdenosine inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine]PMID:9353301
Slc29a1multiple interactionsISOSLC29A1 (Homo sapiens)6480464CTDcilostazol inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Dipyridamole inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; draflazine inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Ethanol promotes the reaction [SLC29A1 protein alternative form results in increased uptake of Adenosine]; Ethanol promotes the reaction [SLC29A1 protein results in increased uptake of Adenosine]; Ticagrelor inhibits the reaction [SLC29A1 protein results in increased uptake of Adenosine]PMID:21283641 PMID:28041785
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