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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620945
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp8
Name: caspase 8
Acc ID: CHEBI:16335
Term: adenosine
Definition: A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond.
Chemical ID: MESH:D000241
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp8increases activityEXP 6480464CTDAdenosine results in increased activity of CASP8 proteinPMID:16469385
Casp8increases activityISOCASP8 (Homo sapiens)6480464CTDAdenosine results in increased activity of CASP8 proteinPMID:17303086
Casp8multiple interactionsISOCASP8 (Homo sapiens)6480464CTDDipyridamole inhibits the reaction [Adenosine results in increased activity of CASP8 protein]PMID:17303086
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