GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gclm | decreases expression | EXP | | 6480464 | CTD | Lithocholic Acid results in decreased expression of GCLM mRNA | PMID:29794447 | Gclm | multiple interactions | EXP | | 6480464 | CTD | [Lithocholic Acid results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA; Vardenafil Dihydrochloride inhibits the reaction [Lithocholic Acid results in decreased expression of GCLM mRNA] | PMID:17724089 PMID:29794447 | Gclm | affects expression | ISO | GCLM (Homo sapiens) | 6480464 | CTD | Lithocholic Acid affects the expression of GCLM mRNA; Lithocholic Acid affects the expression of GCLM protein | PMID:20146260 | Gclm | increases expression | ISO | GCLM (Homo sapiens) | 6480464 | CTD | Lithocholic Acid results in increased expression of GCLM protein | PMID:17724089 | Gclm | multiple interactions | ISO | GCLM (Homo sapiens) | 6480464 | CTD | [Lithocholic Acid results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNA; [Lithocholic Acid results in increased expression of GCLM protein] which results in increased abundance of Glutathione; Buthionine Sulfoximine inhibits the reaction [[Lithocholic Acid results in increased expression of GCLM protein] which results in increased abundance of Glutathione] | PMID:17724089 | |
Go Back to source page | Continue to Ontology report |