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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708427
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2d1
Name: cytochrome P450, family 2, subfamily d, polypeptide 1
Acc ID: CHEBI:16325
Term: lithocholic acid
Definition: A monohydroxy-5beta-cholanic acid with a alpha-hydroxy substituent at position 3. It is a bile acid obtained from chenodeoxycholic acid by bacterial action.
Chemical ID: MESH:D008095
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases metabolic processingEXP 6480464CTDCYP2D1 protein results in increased metabolism of Lithocholic Acid

PMID:18039809
multiple interactionsEXP 6480464CTD[CYP2D1 protein results in increased metabolism of Lithocholic Acid] which results in increased chemical synthesis of Lithocholic Acid analog

PMID:18039809
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