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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2325051
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lpcat2
Name: lysophosphatidylcholine acyltransferase 2
Acc ID: CHEBI:16325
Term: lithocholic acid
Definition: A monohydroxy-5beta-cholanic acid with a alpha-hydroxy substituent at position 3. It is a bile acid obtained from chenodeoxycholic acid by bacterial action.
Chemical ID: MESH:D008095
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lpcat2increases expressionISOLpcat2 (Mus musculus)6480464CTDLithocholic Acid results in increased expression of LPCAT2 mRNAPMID:21480330 PMID:23034213
Lpcat2multiple interactionsISOLpcat2 (Mus musculus)6480464CTDNR1H4 protein promotes the reaction [Lithocholic Acid results in increased expression of LPCAT2 mRNA]; SMAD3 protein promotes the reaction [Lithocholic Acid results in increased expression of LPCAT2 mRNA]PMID:21480330 PMID:23034213
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