GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcc4 | decreases expression | EXP | | 6480464 | CTD | Lithocholic Acid results in decreased expression of ABCC4 mRNA | PMID:17256725 | Abcc4 | increases expression | EXP | | 6480464 | CTD | Lithocholic Acid results in increased expression of ABCC4 mRNA | PMID:18032408 PMID:20977460 PMID:23034213 | Abcc4 | multiple interactions | EXP | | 6480464 | CTD | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [Lithocholic Acid results in increased expression of ABCC4 mRNA]; [Lithocholic Acid co-treated with 1,4-bis(2-(3,5-dichloropyridyloxy))benzene] results in increased expression of ABCC4 protein; [Lithocholic Acid co-treated with oltipraz] results in increased expression of ABCC4 protein; Lithocholic Acid promotes the reaction [NR1H3 protein results in increased expression of ABCC4 mRNA]; NFE2L2 protein promotes the reaction [Lithocholic Acid results in increased expression of ABCC4 mRNA]; SMAD3 protein promotes the reaction [Lithocholic Acid results in increased expression of ABCC4 mRNA] | PMID:17256725 PMID:18032408 PMID:20977460 PMID:23034213 | |
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