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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3369
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppara
Name: peroxisome proliferator activated receptor alpha
Acc ID: CHEBI:16285
Term: phytanic acid
Definition: A branched-chain saturated fatty acid consisting of hexadecanoic acid carrying methyl substituents at positions 3, 7, 11 and 15.
Chemical ID: MESH:D010831
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pparaaffects bindingISORGD:7373096480464CTDPhytanic Acid binds to PPARA protein

PMID:23843199
Pparamultiple interactionsISORGD:7326386480464CTDPPARA protein affects the reaction [Phytanic Acid results in increased expression of FABP1 mRNA]

PMID:10191295
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.