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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10451
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2e1
Name: cytochrome P450, family 2, subfamily e, polypeptide 1
Acc ID: CHEBI:16260
Term: 2-nitrophenol
Definition: A member of the class of 2-nitrophenols that is phenol in which one of the hydrogens that is ortho to the hydroxy group has been replaced by a nitro group.
Chemical ID: MESH:C045573
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2e1affects chemical synthesisISOCYP2E1 (Homo sapiens)6480464CTDCYP2E1 protein affects the chemical synthesis of 2-nitrophenolPMID:11409192
Cyp2e1affects chemical synthesisISOCyp2e1 (Rattus norvegicus)6480464CTDCYP2E1 protein affects the chemical synthesis of 2-nitrophenolPMID:11409192
Cyp2e1increases oxidationISOCYP2E1 (Homo sapiens)6480464CTDCYP2E1 protein results in increased oxidation of 2-nitrophenolPMID:17159769
Cyp2e1increases oxidationISOCyp2e1 (Rattus norvegicus)6480464CTDCYP2E1 protein results in increased oxidation of 2-nitrophenolPMID:20027144
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