GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | multiple interactions | EXP | | 6480464 | CTD | Quercetin inhibits the reaction [[[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 mRNA] which results in increased chemical synthesis of Nitric Oxide]; Quercetin inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased abundance of Nitric Oxide]; Quercetin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] affects the localization of CAV1 protein]; Quercetin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased phosphorylation of JAK1 protein]; Quercetin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; Quercetin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; Quercetin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased phosphorylation of SRC protein]; Quercetin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]; Quercetin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased phosphorylation of TYK2 protein]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP1 protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP6 protein]]; Quercetin inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [IFNG protein results in increased activity of CASP8 protein]]; Quercetin inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA]; Quercetin inhibits the reaction [IFNG protein results in increased expression of NOS2 protein]; Quercetin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein] | PMID:11020457 PMID:15914627 PMID:16171798 PMID:20060843 PMID:22185406 | Ifng | increases expression | ISO | IFNG (Homo sapiens) | 6480464 | CTD | Quercetin results in increased expression of IFNG mRNA; Quercetin results in increased expression of IFNG protein | PMID:12431781 | Ifng | multiple interactions | ISO | Ifng (Rattus norvegicus) | 6480464 | CTD | Quercetin inhibits the reaction [[IL1B protein co-treated with IFNG protein] affects the localization of and results in increased activity of NFKB1 protein]; Quercetin inhibits the reaction [[IL1B protein co-treated with IFNG protein] affects the localization of and results in increased activity of RELA protein]; Quercetin inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in decreased secretion of INS1 protein]; Quercetin inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; Quercetin inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased degradation of NFKBIA protein]; Quercetin inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; Quercetin inhibits the reaction [[IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of BAX protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] affects the localization of RELA protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in decreased expression of NFKBIA protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased cleavage of PARP1 protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Quercetin inhibits the reaction [Cyclophosphamide results in increased expression of IFNG protein]; Quercetin promotes the reaction [[Lipopolysaccharides co-treated with IFNG protein co-treated with TNF protein] results in increased expression of SOD2 protein] | PMID:16366677 PMID:18090225 PMID:23138875 PMID:35906875 | Ifng | multiple interactions | ISO | IFNG (Homo sapiens) | 6480464 | CTD | Quercetin inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of ICAM1 protein]; Quercetin inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of NOS2 protein]; Quercetin inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of PTGS2 protein]; Quercetin inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of SELE protein]; Quercetin inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of VCAM1 protein]; Quercetin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased abundance of Nitric Oxide]; Quercetin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK1 protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of MAPK3 protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of RELA protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL8 protein]; Quercetin inhibits the reaction [[TNF protein co-treated with IL1B protein co-treated with IFNG protein] inhibits the reaction [Glucose results in increased secretion of INS1 protein]] | PMID:18394220 PMID:21756928 PMID:22698256 PMID:23138875 | | ||||||||||||||||||||||
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