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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733019
Species: Homo sapiens
RGD Object: Gene
Symbol: PRDX2
Name: peroxiredoxin 2
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PRDX2increases expressionEXP 6480464CTDQuercetin results in increased expression of PRDX2 mRNA; Quercetin results in increased expression of PRDX2 proteinPMID:17292933 PMID:22996356
PRDX2multiple interactionsEXP 6480464CTD[Quercetin co-treated with Paraquat] results in increased expression of PRDX2 mRNA; Quercetin inhibits the reaction [Benzo(a)pyrene results in decreased expression of PRDX2 protein]PMID:17292933 PMID:22996356
PRDX2multiple interactionsISOPrdx2 (Mus musculus)6480464CTDQuercetin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PRDX2 mRNA]PMID:25471833
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