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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727948
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppargc1b
Name: PPARG coactivator 1 beta
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargc1bmultiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [Atorvastatin affects the expression of PPARGC1B mRNA]PMID:21775390
Ppargc1bincreases expressionISOPPARGC1B (Homo sapiens)6480464CTDQuercetin results in increased expression of PPARGC1B mRNAPMID:32530119
Ppargc1bmultiple interactionsISOPPARGC1B (Homo sapiens)6480464CTDTamoxifen inhibits the reaction [Quercetin results in increased expression of PPARGC1B mRNA]PMID:32530119
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