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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708377
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Zbtb10
Name: zinc finger and BTB domain containing 10
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:13489516480464CTDQuercetin results in decreased expression of ZBTB10 mRNA

PMID:21632981
multiple interactionsISORGD:13489516480464CTD[Quercetin co-treated with hyperoside] inhibits the reaction [MIR27A mRNA results in decreased expression of ZBTB10 mRNA], [Quercetin co-treated with hyperoside] results in increased expression of ZBTB10 mRNA, [resveratrol co-treated with Quercetin] results in increased expression of ZBTB10 mRNA, MIR27A mRNA inhibits the reaction [[Quercetin co-treated with hyperoside] results in increased expression of ZBTB10 mRNA]

PMID:23530649, PMID:24173369
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.