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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628627
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2b3
Name: cytochrome P450, family 2, subfamily b, polypeptide 3
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2b3affects expressionISOCyp2b10 (Mus musculus)6480464CTDQuercetin affects the expression of CYP2B10 mRNAPMID:16455785
Cyp2b3decreases activityISOCyp2b10 (Mus musculus)6480464CTDQuercetin results in decreased activity of CYP2B10 proteinPMID:18420780
Cyp2b3multiple interactionsISOCyp2b10 (Mus musculus)6480464CTD[Dietary Fats co-treated with Quercetin] affects the expression of CYP2B10 mRNAPMID:25047408
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